Pełna lista utworów znajdujących się na płytach Rock Band 2. 84 piosenki ułożone chronologicznie dekadami według pierwszej daty wydania. Wszystkie utwory w oryginalnych wykonaniach.

1960s

Norman Greenbaum - "Spirit in the Sky"
The Who - "Pinball Wizard"

1970s

AC/DC - "Let There Be Rock"
Allman Brothers - "Ramblin' Man"
Bad Company - "Shooting Star"
Blondie - "One Way or Another"
Bob Dylan - "Tangled Up in Blue"
Cheap Trick - "Hello There"
Elvis Costello - "Pump It Up"
Fleetwood Mac - "Go Your Own Way"
Jethro Tull - "Aqualung"
Journey - "Anyway You Want It"
Kansas - "Carry On Wayward Son"
Rush - "The Trees"
Squeeze - "Cool for Cats"
Steely Dan - "Bodhitsattya"
Steve Miller Band - "Rock'n Me"
Talking Heads - "Psycho Killer"
The Guess Who - "American Woman"

1980s

Billy Idol - "White Wedding Pt. I"
Bon Jovi - "Livin' on a Prayer"
Devo - "Uncontrollable Urge"
Duran Duran - "Hungry Like the Wolf"
Jane's Addiction - "Mountain Song"
Joan Jett - "Bad Reputation"
Megadeth - "Peace Sells"
Metallica - "Battery"
Motorhead - "Ace of Spades"
Ratt - "Round & Round"
Sonic Youth - "Teenage Riot"
Survivor - "Eye of the Tiger"
The Go-Go's - "We Got the Beat"
The Grateful Dead - "Alabama Getaway"
The Replacements - "Alex Chilton"

1990s

Alanis Morissette - "You Oughta Know"
Alice in Chains - "Man in the Box"
Beastie Boys - "So Whatcha Want"
Bikini Kill - "Rebel Girl"
Dinosaur Jr. - "Feel the Pain"
Foo Fighters - "Everlong"
Judas Priest - "Painkiller"
L7 - "Pretend We're Dead"
Lit - "My Own Worst Enemy"
Lush - "De-Luxe"
Mighty Mighty Bosstones - "Where'd You Go"
Nirvana - "Drain You"
Pearl Jam - "Alive"
Presidents of the USA - "Lump"
Rage Against the Machine - "Testify"
Red Hot Chili Peppers - "Give it Away"
Smashing Pumpkins - "Today"
Social Distortion - "I Was Wrong"
Soundgarden - "Spoonman"
Testament - "Souls of Black"
The Muffs - "Kids in America"
The Offspring - "Come Out & Play (Keep 'em Separated)"

2000s

AFI - "Girl's Gone Grey"
Avenged Sevenfold - "Almost Easy"
Beck - "E-Pro"
Disturbed - "Down with the Sickness"
Dream Theater - "Panic Attack"
Guns N' Roses - "Shackler's Revenge"
Interpol - "PDA"
Jimmy Eat World - "The Middle"
Lacuna Coil - "Our Truth"
Linkin Park - "One Step Closer"
Mastodon - "Colony of Birchmen"
Modest Mouse - "Float On"
Panic at the Disco - "Nine in the Afternoon"
Paramore - "That's What You Get"
Rise Against - "Give it All"
Silversun Pickups - "Lazy Eye"
System of a Down - "Chop Suey"
Tenacious D - "Master Exploder"
The Donnas - "New Kid in School"

Bonus

Abnormality - "Visions"
Anarchy Club - "Get Clean"
Bang Camaro - "Night Lies"
Breaking Wheel - "Shoulder to the Plow"
The Libyans - "Neighborhood"
The Main Drag - "A Jagged Gorgeous Winter"
Speck - "Conventional Lover"
The Sterns - "Supreme Girl"
That Handsome Devil - "Rob the Prez-O-Dent"